刘龙丁，1969年生，籍贯内蒙古呼和浩特，医学生物学研究所研究员，博士生导师，研究方向病毒疫苗学。1987年考入云南大学微生物学专业，1991年获得学士学位。1999年在中国协和医科大学免疫学专业攻读硕士学位，从事病毒与宿主相互作用研究。2005年在老虎机游戏免疫学专业攻读博士学位，从事病毒免疫学研究。2008年受聘为中国医学科学院研究员，从事肠道病毒和呼吸道病毒疫苗研发评价。

呼吸道病毒感染致病机制研究及疫苗研发；肠道病毒感染机制研究及疫苗研发；以单克隆抗体为导向的新型疫苗设计和评价；以单细胞测序技术为基础的新型疫苗评价体系的探究。

老虎机游戏

1. Zheng H#, Chen Y#, Li J#, Li H#, Zhao X#, Li J#, Yang F, Li Y, Liu C, Qin L, Zuo Y, Zhang Q, He Z*, Shi H*, Li Q*, Liu L*. Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques. Cell Rep. 2022 May 24;39(8):110864. (IF=9.995)

2. Li H#, Zhao X#, Zhao Y#, Li J#, Zheng H#, Xue M, Guo L, Zhou J, Yang J, Zuo Y, Chen Y, Yang Z, Fan Q, Qin L, Shi H, Liu L*. H1N1 exposure during the convalescent stage of SARS-CoV-2 infection results in enhanced lung pathologic damage in hACE2 transgenic mice. Emerg Microbes Infect. 2021 Dec;10(1):1156-1168. (IF=19.568)

3. Guo L, Li N, Yang Z, Li H, Zheng H, Yang J, Chen Y, Zhao X, Mei J, Shi H, Worthen GS, Liu L. Role of CXCL5 in Regulating Chemotaxis of Innate and Adaptive Leukocytes in Infected Lungs Upon Pulmonary Influenza Infection. Front Immunol. 2021 Nov 18;12:785457. (IF=8.786)

4. Zheng H#, Li H#, Guo L#, Liang Y#, Li J#, Wang X, Hu Y, Wang L, Liao Y, Yang F, Li Y, Fan S, Li D, Cui P, Wang Q, Shi H, Chen Y, Yang Z, Yang J, Shen D, Cun W, Zhou X, Dong X, Wang Y, Chen Y, Dai Q, Jin W, He Z*, Li Q*, Liu L*. Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression. PLoS Pathog. 2020 Nov 12;16(11):e1008949. (IF=6.823)

5. Guo L#, Li N#, Li W, Zhou J, Ning R, Hou M*, Liu L*. New hemagglutinin dual-receptor-binding pattern of a human-infecting influenza A (H7N9) virus isolated after fifth epidemic wave. Virus Evol. 2020 Apr 20;6(1):veaa021. (IF=7.989)

6. Zheng H#, Wang J#, Li B#, Guo L, Li H, Song J, Yang Z, Li H, Fan H, Huang X, Long H, Cheng C, Chu M, He Z, Yu W, Li J, Gao Y, Ning R, Li N, Yang J, Wu Q, Shi H, Sun M*, Liu L*. A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice. J Immunol. 2018 Nov 1;201(9):2557-2569. (IF=4.718)

7. Guo L#, Feng K#, Wang YC#, Mei JJ, Ning RT, Zheng HW, Wang JJ, Worthen GS, Wang X, Song J, Li QH, Liu LD*. Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection. Mucosal Immunol. 2017 Nov;10(6):1529-1541. (IF=7.36)

8. Liu L#, Mo Z#, Liang Z#, Zhang Y, Li R, Ong KC, Wong KT, Yang E, Che Y, Wang J, Dong C, Feng M, Pu J, Wang L, Liao Y, Jiang L, Tan SH, David P, Huang T, Zhou Z, Wang X, Xia J, Guo L, Wang L, Xie Z, Cui W, Mao Q, Liang Y, Zhao H, Na R, Cui P, Shi H, Wang J*, Li Q*. Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations. BMC Med. 2015 Sep 17;13:226. (IF=8.005)

9. Li R#, Liu L#, Mo Z#, Wang X#, Xia J#, Liang Z#, Zhang Y, Li Y, Mao Q, Wang J, Jiang L, Dong C, Che Y, Huang T, Jiang Z, Xie Z, Wang L, Liao Y, Liang Y, Nong Y, Liu J, Zhao H, Na R, Guo L, Pu J, Yang E, Sun L, Cui P, Shi H, Wang J*, Li Q*. An inactivated enterovirus 71 vaccine in healthy children. N Engl J Med. 2014 Feb 27;370(9):829-37. (IF=53.125, ESI)

10. Liu L#, Zhang Y#, Wang J, Zhao H, Jiang L, Che Y, Shi H, Li R, Mo Z, Huang T, Liang Z, Mao Q, Wang L, Dong C, Liao Y, Guo L, Yang E, Pu J, Yue L, Zhou Z, Li Q*. Study of the integrated immune response induced by an inactivated EV71 vaccine. PLoS One. 2013;8(1):e54451. (IF=4.078, F1000）